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Ideal for men who train hard, travel often or need an extra metabolic boost, this therapy complements your lifestyle and helps your body make the most of your effort. Beneficial for men with confirmed hormone deficiency and performance-focused goals. This option enhances muscle strength, bone health and overall vitality. If you’re ready to take the first step towards a happier, healthier you, contact your local Gameday Men’s Health today to schedule a consultation.
DEPO-Testosterone Injection, for intramuscular injection, contains testosterone cypionate which is the oil-soluble 17 (beta)-cyclopentylpropionate ester of the androgenic hormone testosterone. These supplements can complement testosterone therapy, support metabolic health, improve energy and recovery, and help optimize overall wellness when used under provider guidance. Testosterone cypionate remains one of the most commonly prescribed forms of testosterone therapy in men’s health practice.
When testosterone is low, it affects far more than physical performance. RxList does not provide medical advice, diagnosis or treatment. The steroid-receptor complex is transported to the nucleus where it initiates transcription events and cellular changes related to androgen action.
Testosterone cypionate, or testosterone 17β-cyclopentylpropionate, is a synthetic androstane steroid and a derivative of testosterone. For reference, testosterone enanthate has an elimination half-life of 4.5 days and a mean residence time of 8.5 days and requires frequent administration of approximately once per week. The drug's safety in andropause (late-onset hypogonadism in men) has not yet been established, and there are concerns that it may escalate the risks of benign prostatic hyperplasia, prostate cancer and heart diseases. It is currently FDA approved for the treatment of primary or hypogonadotropic hypogonadism (either congenital or acquired). The drug is a controlled substance in many countries and so non-medical use is generally illicit. Along with testosterone enanthate, testosterone undecanoate, and testosterone propionate, it is one of the most commonly used testosterone esters. Because of this, it is considered to be a natural and bioidentical form of testosterone.
The reasons cited were limited efficacy (about one additional sexually satisfying event per month), concerns about safety and potential adverse effects with long-term therapy, and concerns about inappropriate off-label use. In 2003, the FDA rejected Intrinsa, a 300 μg/day testosterone patch for the treatment of sexual dysfunction in postmenopausal women. For this reason, and due to the unknown health effects and safety of testosterone therapy, its use may be inappropriate. A subsequent 2017 systematic review and meta-analysis of studies including over 3,000 postmenopausal women with HSDD similarly found that short-term transdermal testosterone therapy was effective in improving multiple domains of sexual function. Testosterone therapy is effective in the short-term for the treatment of hypoactive sexual desire disorder (HSDD) in women.
In addition to injections, your provider may recommend periodic blood testing every few months to monitor testosterone levels, red blood cell counts, cholesterol, and other important markers. Stable hormone levels often mean fewer side effects and a more consistent improvement in symptoms. Because of the potential risk of serious adverse health effects, this drug should not be used for such purpose.
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